Contraindicated (one)cobicistat will boost the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.itraconazole will boost the level or effect of sildenafil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Closely. Not suggested all through and a couple of weeks following itraconazo
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Keep track of hypertension response to sildenafil in people getting concurrent blood pressure reducing therapy.Watch Closely (1)pindolol boosts effects of sildenafil by additive vasodilation. Use Warning/Watch. Sildenafil has systemic vasodilatory properties and will additional lower hypertension in patients using antihypertensive prescription drug